The KDIGO Guideline Methodology Fellowship is a training program for early-career researchers, providing hands-on experience in guideline development. Fellows work closely with the Methods Committee to learn about protocol development, question refinement, evidence review, GRADE, stakeholder engagement, and the development of clinical practice guidelines.
The KDIGO Methods Manual is a comprehensive document that outlines the processes and standards used in developing KDIGO Guidelines. It includes a description of policies and procedures around the guideline development process, roles and responsibilities of all parties involved in the process, evidence review processes including grading recommendations, and information on guideline writing and publication.
Public Review is the period during which KDIGO shares a guideline Scope of Work, draft clinical practice guideline, or Controversies Conference Scope of Work (SOWs) with the public for comment. Any interested stakeholder, including clinicians, researchers, patients, policymakers, and industry representatives, is invited to provide feedback. Public Review periods typically last from two to six
KDIGO follows a rigorous Disclosure of Interest (DOI) and conflict management policy. All participants, including WG members, ERTs, and the Methods Committee, must declare financial and nonfinancial interests. DOIs are classified by risk level (high, moderate, low), and those with high-risk conflicts may be recused from decision-making on a particular topic. Updates are required at
KDIGO hires an Evidence Review Team (ERT) as part of the development process for each of its guidelines. Before selecting an ERT, KDIGO issues a Request for Proposal based on the Scope of Work (SOW). Institutions with expertise in evidence synthesis submit proposals detailing their assessment of the key clinical questions based on the SOW,
Guidelines are developed using a standardized, transparent methodology that adheres to international standards for systematic reviews, evidence synthesis, and guideline development, such as the National Academy of Medicine’s recommendations and the AGREE II checklist. Guidelines undergo a robust peer and public review process. There is an open Public Review period for both the guideline Scope
KDIGO follows a comprehensive, evidence-based guideline development process in line with international standards for systematic reviews, evidence synthesis, and guideline development. This includes formulation of clinical questions using PICOS criteria (Population, Intervention, Comparator, Outcomes, Study Design), a formal systematic review and synthesis of the literature by an independent Evidence Review Team (often referred to as