The Kidney Disease: Improving Global Outcomes (KDIGO) 2008 Clinical Practice Guideline on the Prevention, Diagnosis, Evaluation and Treatment of Hepatitis C (HCV) in Chronic Kidney Disease (CKD) aims to assist practitioners in the detection and evaluation of HCV in patients on dialysis or with CKD; treatment of HCV in patients with CKD; management of HCV-infected patients before and after kidney transplantation; diagnosis and management of kidney diseases associated with HCV; and prevention of HCV transmission in hemodialysis units. Guideline development followed an explicit process of evidence review and appraisal in which guideline recommendations are formulated and based on systematic reviews of relevant trials. The appraisal of the quality of evidence and the strength of recommendations followed the GRADE approach. Limitations of the evidence and gaps in knowledge are discussed and specific topical questions are proposed as part of future research agenda.
In citing this document, the following format should be used: Kidney Disease: Improving Global Outcomes. KDIGO clinical practice guidelines for the prevention, diagnosis, evaluation, and treatment of Hepatitis C in chronic kidney disease. Kidney International 2008; 73 (Suppl 109): S1–S99.
European Renal Best Practice
International Society of Nephrology
United Kingdom Renal Association
DISCLAIMER: USE OF THE CLINICAL PRACTICE GUIDELINES
This Clinical Practice Guideline is based upon the best information available at the time of publication. The recommendations are designed to provide information and assist decision-making. They are not intended to define a standard of care, and should not be construed as one. Neither should they be interpreted as prescribing an exclusive course of management. Variations in practice will inevitably and appropriately occur when clinicians take into account the needs of individual patients, available resources, and limitations unique to an institution or type of practice. Every health care professional making use of this Guideline is responsible for evaluating the appropriateness of applying them in the setting of any particular clinical situation. The recommendations for research contained within this document are general and do not imply a specific protocol.