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CKD-Mineral and Bone Disorder (CKD-MBD)


The Kidney Disease: Improving Global Outcomes (KDIGO) 2017 Clinical Practice Guideline Update for the Diagnosis, Evaluation, Prevention, and Treatment of chronic kidney diseasemineral and bone disorder (CKD-MBD) represents a selective update of the prior guideline published in 2009. This update, along with the 2009 publication, is intended to assist the practitioner caring for adults and children with CKD, those on chronic dialysis therapy, or individuals with a kidney transplant. Specifically, the topic areas for which updated recommendations are issued include diagnosis of bone abnormalities in CKD-MBD; treatment of CKD-MBD by targeting phosphate lowering and calcium maintenance, treatment of abnormalities in parathyroid hormone in CKD-MBD; treatment of bone abnormalities by antiresorptives and other osteoporosis therapies; and evaluation and treatment of kidney transplant bone disease. Development of this guideline update followed an explicit process of evidence review and appraisal. Treatment approaches and guideline recommendations are based on systematic reviews of relevant trials, and appraisal of the quality of the evidence and the strength of recommendations followed the GRADE (Grading of Recommendations Assessment, Development, and Evaluation) approach. Limitations of the evidence are discussed, with areas of future research also presented.

 

CITATION
In citing this document, the following format should be used: Kidney Disease: Improving Global Outcomes (KDIGO) CKD-MBD Update Work Group. KDIGO 2017 Clinical Practice Guideline Update for the Diagnosis, Evaluation, Prevention, and Treatment of Chronic Kidney Disease–Mineral and Bone Disorder (CKD-MBD). Kidney Int Suppl. 2017;7:1–59.


Translations

2009 CKD-MBD Guideline Translations

 

Arabic

الأرشادات السريرية العملية للوقاية من وتشخيص وتقيم وعلاج إختلال المعادن
.والعظم – الناتج عن الداء الكلوي المزمن

 

Chinese (Mandarin)

KDIGO 慢性肾脏病-矿物质和骨异常诊断、评价、预防和治疗的临床实践指南

 

French

RECOMMANDATIONS KDIGO DE BONNES PRATIQUES CLINIQUESPOUR LE DIAGNOSTIC, L’EVALUATION, LA PREVENTION ET LE TRAITEMENT DES TROUBLES MINERAUX ET OSSEUX ASSOCIES AUX MALADIES RENALES CHRONIQUES (TMO-MRC)

 

German

KDIGO-Leitlinien zu den Störungen des Mineral- und Knochenhaushalts bei chronischer Nierenerkrankung (Part 1)

KDIGO-Leitlinien zu den Störungen des Mineral- und Knochenhaushalts bei chronischer Nierenerkrankung (Part 2)

 

Greek

ΚΑΤΕΥΘΥΝΤΗΡΙΕΣ ΟΔΗΓΙΕΣ ΤΗΣ ΟΡΓΑΝΩΣΗΣ KDIGO ΓΙΑ ΤΗ ΔΙΑΓΝΩΣΗ, ΤΗΝ ΕΚΤΙΜΗΣΗ, ΤΗΝ ΠΡΟΛΗΨΗ ΚΑΙ ΤΗ ΘΕΡΑΠΕΙΑ ΤΗΣ ΔΙΑΤΑΡΑΧΗΣ ΤΟΥ ΜΕΤΑΒΟΛΙΣΜΟΥ ΤΩΝ ΟΣΤΩΝ ΚΑΙ ΤΩΝ ΜΕΤΑΛΛΙΚΩΝ ΣΤΟΙΧΕΙΩΝ ΣΤΗΝ ΧΡΟΝΙΑ ΝΕΦΡΙΚΗ ΝΟΣΟ (ΔΟΜ-ΧΝΝ)

 

Italian

LINEE GUIDA KDIGO PER LA DIAGNOSI, LA VALUTAZIONE, LA PREVENZIONE E IL TRATTAMENTO DELLA PATOLOGIA DEL METABOLISMO MINERALE E OSSEO SECONDARIA ALLA MALATTIA RENALE CRONICA (CKD-MBD)

 

Japanese

CKD-MBD の診断、検査法、予防および治療に関するKDIGO 診療ガイドライン

 

Portuguese

KDIGO – DIRETRIZES CLÍNICAS PARA O DIAGNÓSTICO, AVALIAÇÃO, PREVENÇÃO E TRATAMENTO DO DISTÚRBIO MINERAL E ÓSSEO NA DOENÇA RENAL CRÔNICA (CKD-MBD)

 

Russian

ПРАКТИЧЕСКИЕ РЕКОМЕНДАЦИИ KDIGO ПО ДИАГНОСТИКЕ, ПРОФИЛАКТИКЕ И ЛЕЧЕНИЮ МИНЕРАЛЬНЫХ И КОСТНЫХ НАРУШЕНИЙ ПРИ ХРОНИЧЕСКОЙ БОЛЕЗНИ ПОЧЕК (ХБП-МКН)

 

Spanish

GUIAS DE PRACTICA CLINICA PARA EL DIAGNOSTICO, EVALUACION, PREVENCION Y TRATAMIENTO DE LOS TRASTORNOS MINERALES Y DEL HUESO EN LA ENFERMEDAD RENAL CRONICA (CKD-MBD)

 

Turkish

KDIGO KRONİK BÖBREK HASTALIĞI – MİNERAL VE KEMİK BOZUKLUKLARI (KBH-MKB) TANI, DEĞERLENDİRME, ÖNLEME VE TEDAVİ KLİNİK UYGULAMA KILAVUZU



DISCLAIMER: USE OF THE CLINICAL PRACTICE GUIDELINES

This Clinical Practice Guideline is based upon the best information available at the time of publication. The recommendations are designed to provide information and assist decision-making. They are not intended to define a standard of care, and should not be construed as one. Neither should they be interpreted as prescribing an exclusive course of management. Variations in practice will inevitably and appropriately occur when clinicians take into account the needs of individual patients, available resources, and limitations unique to an institution or type of practice. Every health care professional making use of this Guideline is responsible for evaluating the appropriateness of applying them in the setting of any particular clinical situation. The recommendations for research contained within this document are general and do not imply a specific protocol.