Guidelines are developed using a standardized, transparent methodology that adheres to international standards for systematic reviews, evidence synthesis, and guideline development, such as the National Academy of Medicine’s recommendations and the AGREE II checklist. Guidelines undergo a robust peer and public review process. There is an open Public Review period for both the guideline Scope of Work and draft guideline, whereby stakeholders may provide their feedback on the content of the guideline in development. KDIGO guidelines also undergo peer review at the journal’s publication level. KDIGO does not accept industry funding for guidelines and implements strict policies for the management of disclosures of interest for all participants.