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The KDIGO Controversies Conference on the Role of Complement in Kidney Disease will be held in Florence, Italy from Thursday, September 29 to Sunday, October 2, 2022. This conference will gather a global panel of multidisciplinary clinical and scientific expertise (i.e., pediatrics, rheumatology, complement basic research, renal pathology, genetics) and a motivated group of patient representatives to define the role of complement in a spectrum of kidney diseases including glomerular disorders and diabetic nephropathy.

For each disease that will be addressed, the evidence indicating whether complement plays a primary or secondary role in their etiologies will be reviewed. The value of biomarkers of complement activity in monitoring disease course and whether specific drivers (i.e., genetic or acquired) dysregulate complement activity will be critically examined, as will the potential impact/role of the glomerular microenvironment in contributing to the complement response.

The KDIGO Controversies Conference on the Role of Complement in Kidney Disease will be co-chaired by Richard Smith (USA), and Marina Vivarelli (Italy).