(Brussels, Belgium) – – – Kidney Disease: Improving Global Outcomes (KDIGO) announced that Johns Hopkins University in Baltimore, USA has been chosen as the Evidence Review Center for its latest clinical practice guideline update project.

The KDIGO guideline on Chronic Kidney Disease and Mineral and Bone Disorders (CKD-MBD) was published in 2009 and will be updated to reflect scientific developments since publication. KDIGO will work with Dr. Karen Robinson, Director of the Evidence Based Practice Center at Johns Hopkins, and her team to assemble evidence for consideration by a work group of internationally recognized scientists.

The original guideline was published in Kidney International and has had a major impact for patients with CKD-MBD around the world. The guideline deals with many of the complex issues faced by clinicians as they treat CKD-related bone and mineral co-morbidities. These problems affect patients at all stages of CKD and pose serious challenges to the outcome of their care.

In October 2013, KDIGO held a major Controversies Conference in Madrid, Spain to examine progress since the CKD-MBD guideline was published. The attendees, made up of some 65 international experts in CKD-MBD, recommended that several sections of the guideline be reassessed as soon as possible. The update process is now underway, co-chaired by Drs. Mary Leonard of Stanford University and Markus Ketteler of Klinikum Coburg GmbH. 13 work group members from eight countries will work on the project throughout 2015.

KDIGO develops its global guidelines in order to translate the latest science into usable practice recommendations. A major challenge in guideline development and publication is keeping the recommendations current in light of new studies and published data. KDIGO is committed to an update process that constantly monitors the medical literature for new evidence related to KDIGO guideline topics.

KDIGO co-chair Dr. Bertram Kasiske said, “KDIGO will serve the global kidney community by providing up-to-date practice recommendations based on all the available new science which will help clinical decision-making. Our goal of improving outcomes depends on continuous surveillance of the field and action to update recommendations when the science changes.”

“These should be living documents. Scientific discovery doesn’t stand still and neither will KDIGO. Other updates will follow as need dictates. Electronic versions of our guidelines enable them to be more accessible throughout the world and make updating easier,” said Dr. David Wheeler, co-chair of KDIGO.

KDIGO has published nine guidelines in the past decade and has held 19 Controversies Conferences. Each is meant to aid kidney disease practice decisions in the best interest of patients and the medical community. New guidelines are under development and numerous Controversies Conferences are currently being planned.


KDIGO is a Belgian foundation committed to developing and implementing nephrology guidelines that improve patient outcomes on a global basis.

For further information please contact KDIGO at [email protected].



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