KDIGO convened a Controversies Conference on Diagnosis and Management of Patients with Fabry Nephropathy from October 15-17, 2015 in Dublin, Ireland. The objective of this conference was to assess the current state of knowledge related to cell and organ damage by Fabry specific and unspecific mechanisms and its treatment; approaches to screening and diagnosis as well as biochemical and histological follow-up of Fabry disease; optimal prevention of kidney disease; and management for the reduction of comorbidities such as extrarenal organ involvement. The overarching goal was to summarize the current knowledge gaps and propose a research agenda to resolve standing controversial issues. It is hoped that output from this conference will inform clinicians of the evidence base for present treatment options and help pave the way for future studies in this area.

Drs. Christoph Wanner (University of Würzburg Hospital, Germany) and Raphael Schiffmann (Baylor Research Institute, Dallas, Texas, USA) co-chaired this conference.