San Francisco, USA March, 2014
The intent of the KDIGO Controversies Conference on Iron Management in Chronic Kidney Disease was to gather a global panel of multidisciplinary clinical and scientific expertise to identify key issues relevant to the optimal iron management in CKD. The objective of this conference was to assess our current state of knowledge related to iron metabolism and the mechanisms underlying its pathophysiology in CKD; address key controversial issues concerning the use of iron therapeutic agents in the treatment of anemia in CKD; summarize the outstanding knowledge gaps; and to propose a research agenda to resolve standing controversial issues. This conference aimed to inform clinicians of the evidence base for present treatment options and help pave the way for future studies in this area.
The KDIGO Controversies Conference on Iron Management in Chronic Kidney Disease took place in San Francisco, California, USA on March 28-30, 2014. Drs. Glenn M Chertow (Stanford University School of Medicine, USA) and Iain C Macdougall (King’s College Hospital, UK) co-chaired this conference.
Conference Overview & Objectives
Presenter: Iain Macdougall (Conference Co-Chair)
General Overview of Iron Metabolism
Presenter: Tomas Ganz
Adverse Consequences of Iron Deficiency and the Importance of its Correction
Presenter: Stefan Anker
Regulation of Hepcidin and its Role as a Diagnostic Tool
Presenter: Dorine Swinkels
Iron Overload in CKD and Effects on Various Tissues
Presenter: Kamyar Kalantar-Zadeh
Iron, Inflammation and Oxidative Stress: Partners in Crime?
Presenter: Peter Stenvinkel
Interplay Between Iron and Inflammatory Processes
Presenter: Peter Bárány
Potential Role of Iron in CVD and Diabetes
Presenter: Nosratola Vaziri
Effects of Iron on the Immune System
Presenter: Gert Mayer
Iron and Risks of Infection: Real or Theoretical?
Presenter: Günter Weiss
Preferred Dosing Regimens for IV Iron
Presenter: Wolfgang Winkelmayer
Mechanisms of Drug Hypersensitivity
Presenter: Andreas Bircher
Management of Iron Hypersensitivity
Presenter: Michael Auerbach
Presenter: Ioav Cabantchik
What is the Ideal Iron and ESA Balance in CKD Anemia Management?
Presenter: Glenn Chertow (Conference Co-Chair)
Iron Management: New Strategies Currently Under Investigation
Presenter: Iain Macdougall (Conference Co-Chair)